Ringer's Lactate with NMN+
Non-Prescription Low-Dose NMN+ Precursor IV Therapy*
Many people, after setting effective levels of NMN+ (often in combination with separate NAD+ IVs), will opt for prescription dosages of 250 mg up to 1000 mg (1 gram) of NMN+ at planned or regular intervals.
Depending on your goals, varying combinations of NAD+ and NMN+ IV Therapy may be prescribed at appropriate intervals.
* Please note the 50, 100, 150 and 200 mg NMN+ IV infusions are entry level / new user / maintenance dosages. Effects are subtle but effective, generally producing increased energy and cognition. Rarely are Herxing effects produced at this level. These doseages are recommened when NMN+ is taken with natural adjuvants (nutrients that increase the effects of NMN+therapy- see below).
Native NMN (Nicotinamide mononucleotide). NMN without the “+” is what is naturally manufactured in the body, known simply as NMN, or what we call native NMN.
NMN+ (β-nicotinamide mononucleotide). The “+” means this is the supplement form of native NMN.
NMN+ is a powerful NAD production stimulant and is more bio-available than NAD+ as it can enter cells more easily and directly. Once inside the cells, NMN+ is quickly converted into NAD. NMN+ provides a more sustained elevation of native NAD levels over time, even with less frequent dosing.
NMN+, or β-nicotinamide mononucleotide, is also derived from Niacin (Vitamin B3), and serves to supplement decreased native NMN, which is also naturally produced in the body, just like native NAD. However, its production decreases as we age. As native NMN levels decline, signs of aging, reduced physical ability, and cognitive decline can begin to appear.
Studies, and BSI experience with patients, have shown that NMN+ Therapy can lead to dramatic improvements in both appearance and bodily functions. This has earned NMN+ the reputation of a “rejuvenating medicine” that is rapidly gaining worldwide acclaim.
Foods like broccoli and cucumbers contain native NAD and NMN, however the amount required to achieve significant benefits would be impractical through diet alone. For example, to ingest just 1 mg of NMN from broccoli, you’d need to consume about 100 kg of broccoli. NMN+ Intravenous (IV) Therapy offers a much more efficient method for delivering this powerful compound into the body.
BSI and Therapure Nutraceuticals manufacture and distribute Pharmaceutical Grade NMN+ (β-nicotinamide mononucleotide), CAS 1094-61-7. Certifications are GMP, ISO 9001, ICP-OES, Farmakope Indonesia VI, British Pharmacopoeia, SNI ISO 21567, USP, FDA.
NMN+ Therapy is administered by slow IV drip, over a period of 60 – 120 minutes, generally once each 1 – 3 days – varies per individual needs. IV therapy allows NMN+ to go directly to individual cell, where it quickly converts to native NAD.
NMN+ (β-nicotinamide mononucleotide), is one of the precursors of native NAD, naturally-occurring in all living organisms. It contains nicotinamide, ribose, and a phosphate group. Therefore, it is an RNA nucleotide. As such, can help to repair damages from mRNA exposures.
During treatment, the patient may use a hand phone, read a good book (consider browsing a copy of the BSI New Patient Guide), or most preferably, we encourage sleep and rest. The body only heals during deep sleep and undisturbed rest.
β-nicotinamide mononucleotide, and other NAD forms are not related nicotine.
We like to combine them in varying ratios depending on goals....
It’s really important to clearly distinguish between Native NAD (NAD) and Native NMN (NMN), against beta NAD (NAD+) and beta NMM (NMN+).
Native NAD (nicotinamide adenine nucleotide) refers to a critical coenzyme found in every cell in the body, and it’s involved in hundreds of metabolic processes. NAD contains nicotinamide ribose and nicotinamide adenine nucleotide bound to nicotinamide ribose through a phosphodiester bond. It’s naturally produced in the body.
Native NMN (nicotinamide mononucleotide) refers to a nucleotide that is most recognized for its role as an intermediate of nicotinamide adenine. NMN contains nicotinamide, ribose, and a phosphate group. It’s naturally produced in the body.
Native NAD levels in the body decrease with the age, but increasing native NAD with NAD+ NMN+, many ailments can improve or be healed.
NAD+ (β-Nicotinamide Adenine Dinucleotide), is a supplemental and medicinal derivative of Niacin (Vitamin B3). NAD, NAD+, NMN+, and Niacin are unrelated to nicotine.
NMN+ (β-nicotinamide mononucleotide), is the precursor of native NAD, a naturally-occurring form of all living organisms. It contains nicotinamide, ribose, and a phosphate group. Therefore, it is an RNA nucleotide. As such, this may help to repair damages from mRNA exposures.
More specifically….
NAD+ IV Therapy: Gives a rapid initial increase in intracellular NAD+ levels, but the decay is more pronounced after the treatment period ends, leading to a faster drop-off in native NAD levels. This is valuable when rapid increase is needed, more so at the beginning of therapy.
NMN+ IV Therapy: Exhibits a slower, more gradual increase in NAD saturation, which is sustained over time. Even after stopping the treatment, the decay is slower, providing a more prolonged elevation in NAD levels. However the body will also be stimulated, over time with added multiple IVs, to begin to produce NAD internally, at more youthful levels.
NMN+ treatment is beneficial to counter effects of aging, chronic depression and brain dysfunction. Naturally occurring levels of native NAD decrease as the body ages. Pure NMN+ Therapy counters many of the effects of aging which are caused by native NAD depletion over time. Overall benefits of NMN+ Therapy include :
NMN+ IV Therapy, often combined with NAD+ IV Therapy, is especially helpful for those addicted to alcohol, nicotine, and opioid drugs. It binds to opioid receptors and reduces the symptoms of withdrawal. It causes the body to replace the vitamins and minerals which have been depleted from substance abuse (with proper nutrition and IV adjuvants. Benefits of NMN+ treatment as part of a holistic recovery strategy include…
Dealing with addiction is rarely easy, whether it be something simple such as sugar (refined white sugar is processed the same way as heroin, and is actually more addictive), or more complicated such as alcohol (alcohol is the most refined form of sugar, hits the brain in 6 seconds). Opiates can be a little easier though, if protocol is followed, and the patient has willingness to proceed.
It is often recommended that NMN+ IV Therapy be combined with addiction counseling and / or participation in a recovery program such as a 12-step group. Sometimes psychotherapy is needed to deal with issues such as mental illness, family dysfunction or PTSD. However, with the help of NMN+ (often combined with NAD+), you can more easily stop using toxic substance(s) and deal with any other issues you have effectively. BSI does not provide psychotherapy at this time, however limited counseling is included.
More NAD = more ATP = more cellular energy = you’ll feel increased energy in your daily activities.
Human body cells, called mitochondria, are often referred to as the “powerhouses” of the cell. They generate adenosine triphosphate or ATP, the molecule that provides energy for cellular processes. This process relies on the presence of NAD. NAD decreases with age.
NMN+ IV therapy, combined with NAD+ IV Therapy) with optional natural nutrients treatment is especially helpful as part of an holistic weight loss treatment.
Native NAD plays a vital role in metabolism by helping convert nutrients into energy the body can use. It does this by acting as a co-factor for several enzymes, that serve to metabolize carbohydrates, fats, and proteins.
Intravenous administration of high-dose β-Nicotinamide Mononucelotide (NMN+ IV Therapy) has emerged as a potent therapy for weight management.
Extensive research indicates NMN+ IV Therapy can enhance mitochondrial function, leading to increased energy expenditure and improved metabolism.
There are numerous therapeutic benefits from intravenous β-nicotinamide mononucleotide (NMN+) therapy for anti-aging. Native NAD declines with age and thus hinders natural repair mechanisms within cells. Raising native intracellular NAD levels is a powerful therapeutic strategy for age-associated degenerative diseases in general and to extend lifespan.
Here is a breakdown of typical dosages for NMN+ IV therapy with optional natural nutrients / adjuvants treatment :
Non-Members, non-prescribed Max Dosage, can be taken with 1 or 2 adjuvants / additional nutrients :
0.05 gr (50 mg) = 45-60 minutes IV total time (can be taken daily)
0.10 gr (100 mg) = 45-60 minutes IV total time (can be taken daily)
0.15 gr (150 mg) = 45-75 minutes IV total time (can be taken each 2 days)
0.20 gr (200 mg) = 75-90 minutes IV total time (can be taken each 2-3 days)
*Please note the 50, 100, 150, and 200 mg NMN+ IV infusions are entry level / new user / maintenance dosages / and may be combined with adjuvants / nutrients. Effects are subtle, generally producing increased energy and cognition. Rarely are Herxing effects produced at this level. If resulting effects are low, then the patient may consider advancing to higher prescribed levels, as seen below.
BSI Members Prescription Dosages, taken as NMN+ in Ringer’s Lactate only (no added adjuvants or nutrients :
0.25 gr (250 mg) = 90-120 minutes IV total time (can be taken each 2-4 days)
0.30 gr (300 mg) = 90-120 minutes IV total time (can be taken each 2-4 days)
0.50 gr (500 mg) = 90-150 minutes total IV time (can be taken each 4–6 days)
0.75 gr (750 mg) = 120-180 minutes IV total time (can be taken each 6-8 days)
1.0 gr (1000 mg) = 150-190 minutes total IV time (can be taken each 7-9 days)
Generally speaking, between 4 and 10 IVs may be prescribed, depending on needs.
A rare side effect of IV NMN+ therapy is muscle tension or ache (if the IV is taken too fast – and the patient is dehydrated). Muscles in the stomach, back, shoulders, legs, and arms can feel sore as if you just did some heavy lifting at a gym. BSI Therapure Nutraceuticals can provide herbal medicines that can help. Mild stretching, heating pads, and essential oils are another remedy to explore.
Imagine a mild wave of pressure rolling over your entire body. For someone who is new to receiving NMN+ Therapy, the wave can be less than comfortable, but don’t let this deter you from receiving the treatment. The wave lasts for a few brief moments before it subsides.
Patients who decide to push their luck and try to cut down their infusion time by increasing the drip rate will experience a rush. Rapid heart rate, headache, and a jolt of energy followed by a wave of pressure, that can be a very unpleasant feeling. Don’t do this.
It is important to remember that NMN+ needs to be administered at a slow rate for health benefits. The more obvious reason is to reduce any discomfort one may experience with a rush of NMN+, but more importantly, native NAD is more readily absorbed into the cells at a slower rate. In other words, a slow drip will have more therapeutic benefit.
If the IV is taken too fast, strong, temporary headache can result.
While not everyone has an emotional experience or breakthrough when receiving the therapy, it is still a good idea to have a box of tissues on hand. Congested sinuses and a runny nose often result from the NMN+. Holistic therapy includes all aspects of the patient’s healing, including emotional, spiritual, physical, mental. Any reactions are usually related to the detox that comes with this therapy.
An increase in appetite can be a hit or miss for most individuals. Some people enjoy snacking during the treatment, whereas some people prefer to fast for the day. Either way, we recommend bringing some healthy, non-sugar snacks (fresh fruit is okay) just in case. Headache or other reactions are less likely too occur if blood glucose is balanced. Addictions are often directly related to sugar consumption.
Proper diet is also of great concern. If consuming addictive foods, such as sugar-filled refined foods, healing will be much more difficult. We recommend a simple diet of whole foods during therapy. So, when combined with a whole foods diet, proper nutrients needed for rebuilding and cleansing of body tissues are provided, addictions are then truly healed. Native NAD requires proper nutrients, not junk food, to stabilize hormones and the endocrine system.
These effects tend to be more prominent in first time users, or with those who take too-large doses. Experienced users tend to not experience ‘inconvenient reactions’ but rather enjoy the benefits of NMN+ Therapy within 24 hours of administration. No inconvenient reactions would indicate a larger dose could be taken at a later date.
Within 1-4 hours after completion of NMN+ IV Therapy
In the event of detox, the patient may on rare occasion experience low-grade fever or dull headache. Remember that the body bakes out pathogens with heat, and these both indicate the therapy is working – body language, your body is telling you therapy is working.
Evening after NMN+ IV Therapy
On rare occasion, the patient may experience cold sweats during sleep, which indicates the body is eliminating toxins that were liberated from skin layers and the circulatory system. This is a very good Herxing reaction, meaning immunities are strong and the body is healing. We are stimulating your body to heal herself, a methodology that is fully suppressed in modern medicine that instead mandates suppression rather than healing.
Next day after completion of NMN+ IV Therapy
Patients may find they need to sleep a little more during the following 24-36 hours. The body only heals during deep sleep and rest. The patient may experience increased urination or other eliminations.
Second day after completion of NMN+ IV therapy
Patients usually begin to feel the benefits of NMN+ therapy by now, which mainly include increased cognition and energy, skin improvement, better muscle tone and excess weight decrease, and a decrease in cravings or addictions.
IMPORTANT: We strongly suggest:
1) The patient eat a meal soon before an IV infusion (avoid sugar), and soon again thereafter.
2) The IV be taken slowly for stronger effect and to lessen Herxing.
3) Try to rest or sleep during the infusion, the body only heals during deep rest.